Validation of numerical simulation for subdural cortical stimulation: Using spherical phantoms and anatomically realistic head phantom

Jinmo Jeong, Donghyeon Kim, Sangdo Jeong, Jonghyun Lee, Euiheon Chung, Sung Chan Jun, Sohee Kim

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

2 Scopus citations

Abstract

The purpose of this study is to investigate the accuracy of numerical simulation for electric brain stimulation. For this, we modelled brains using simple computational models with 2 and 3 shells, with and without realistic head geometry, and performed numerical simulations using finite element method (FEM). The corresponding head phantoms were constructed for the validation of simulation results. We implanted stimulation electrodes in the head phantom, and measured the electric potential induced by the electrodes. When comparing the electric potential obtained from numerical simulations and phantom experiments, both results showed similar trend and amplitude, with a relative difference of 13.64% on average in the realistic head model study. This result demonstrates that predicting the electric potential and its gradient (current density) using computational simulation is reliable with reasonably small deviation from the actual measurement.

Original languageEnglish
Title of host publicationBIOINFORMATICS 2014 - 5th Int. Conf. on Bioinformatics Models, Methods and Algorithms, Proceedings; Part of 7th Int. Joint Conference on Biomedical Engineering Systems and Technologies, BIOSTEC 2014
PublisherSciTePress
Pages136-141
Number of pages6
ISBN (Print)9789897580123
DOIs
StatePublished - 2014
Event5th International Conference on Bioinformatics Models, Methods and Algorithms, BIOINFORMATICS 2014 - Part of 7th International Joint Conference on Biomedical Engineering Systems and Technologies, BIOSTEC 2014 - Angers, Loire Valley, France
Duration: 3 Mar 20146 Mar 2014

Publication series

NameBIOINFORMATICS 2014 - 5th Int. Conf. on Bioinformatics Models, Methods and Algorithms, Proceedings; Part of 7th Int. Joint Conference on Biomedical Engineering Systems and Technologies, BIOSTEC 2014

Conference

Conference5th International Conference on Bioinformatics Models, Methods and Algorithms, BIOINFORMATICS 2014 - Part of 7th International Joint Conference on Biomedical Engineering Systems and Technologies, BIOSTEC 2014
Country/TerritoryFrance
CityAngers, Loire Valley
Period3/03/146/03/14

Keywords

  • Brain Phantom
  • Cortical Stimulation
  • Finite Element Method
  • Numerical Simulation

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