TY - JOUR
T1 - Synthesis of D- and L-myo-inositol 1,2,4,5-tetrakisphosphate and stereoselectivity of the I(1,4,5)P3 receptor binding
AU - Chung, Sung Kee
AU - Shin, Boo Gyo
AU - Chang, Young Tae
AU - Suh, Byung Chang
AU - Kim, Kyong Tai
PY - 1998/3/17
Y1 - 1998/3/17
N2 - D- and L-myo-Inositol 1,2,4,5-tetrakisphosphate [D- and L-I(1,2,4,5)P4], which are analogues of D-myo-Inositol 1,4,5-trisphosphate [D-I(1,4,5)P3], a calcium mobilizing second messenger, were synthesized via resolution of the camphanate ester of a myo-inositol derivative, and the binding affinities to I(1,4,5)P3 receptor were measured.
AB - D- and L-myo-Inositol 1,2,4,5-tetrakisphosphate [D- and L-I(1,2,4,5)P4], which are analogues of D-myo-Inositol 1,4,5-trisphosphate [D-I(1,4,5)P3], a calcium mobilizing second messenger, were synthesized via resolution of the camphanate ester of a myo-inositol derivative, and the binding affinities to I(1,4,5)P3 receptor were measured.
UR - http://www.scopus.com/inward/record.url?scp=0032539716&partnerID=8YFLogxK
U2 - 10.1016/S0960-894X(98)00081-X
DO - 10.1016/S0960-894X(98)00081-X
M3 - Article
C2 - 9871578
AN - SCOPUS:0032539716
SN - 0960-894X
VL - 8
SP - 659
EP - 662
JO - Bioorganic and Medicinal Chemistry Letters
JF - Bioorganic and Medicinal Chemistry Letters
IS - 6
ER -