Polyethylenimine-coated magnetic nanoparticles with improved biocompatibility for hyperthermia

Hao Li, Zhen Jin, Sunghoon Cho, Seong Young Ko, Jong Oh Park, Sukho Park

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

1 Scopus citations

Abstract

Biocomfortable polyethylenimine (PEI) coated Fe3O4 nanoparticles (NPs) have been successfully fabricated for their magnetic hyperthermia performance. After coating with PEI, the sample reveals a tiptop performance of magnetic property and an enhanced biocompatibility. Compared with Fe3O4 NPs, PEI-coated Fe3O4 NPs do not induce notable cell cytotoxic effect at their higher concentration, which indicates that PEI-coated Fe3O4 NPs has improved biocompatibility. The results show that PEI-coated Fe3O4 NPs not only possess effective magnetic property for cancer hyperthermia treatment or gene delivery, but also demonstrates an improved biocompatibility for various biomedical applications.

Original languageEnglish
Title of host publication2016 13th International Conference on Ubiquitous Robots and Ambient Intelligence, URAI 2016
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages466-470
Number of pages5
ISBN (Electronic)9781509008216
DOIs
StatePublished - 21 Oct 2016
Event13th International Conference on Ubiquitous Robots and Ambient Intelligence, URAI 2016 - Xian, China
Duration: 19 Aug 201622 Aug 2016

Publication series

Name2016 13th International Conference on Ubiquitous Robots and Ambient Intelligence, URAI 2016

Conference

Conference13th International Conference on Ubiquitous Robots and Ambient Intelligence, URAI 2016
Country/TerritoryChina
CityXian
Period19/08/1622/08/16

Bibliographical note

Publisher Copyright:
© 2016 IEEE.

Keywords

  • Biocompatibility
  • FeO nanoparticles
  • Magnetic field
  • Polyethylenimine (PEI) hyperthermia

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