ORE1 balances leaf senescence against maintenance by antagonizing G2-like-mediated transcription

Mamoona Rauf; Muhammad Arif; Hakan Dortay; Lilian P. Matallana-Ramírez; Mark T. Waters; Hong Gil Nam; Pyung Ok Lim; Bernd Mueller-Roeber; Salma Balazadeh

doi:10.1038/embor.2013.24

ORE1 balances leaf senescence against maintenance by antagonizing G2-like-mediated transcription

Mamoona Rauf, Muhammad Arif, Hakan Dortay, Lilian P. Matallana-Ramírez, Mark T. Waters, Hong Gil Nam, Pyung Ok Lim, Bernd Mueller-Roeber, Salma Balazadeh

Department of New Biology

Research output: Contribution to journal › Article › peer-review

149 Scopus citations

Abstract

Leaf senescence is a key physiological process in all plants. Its onset is tightly controlled by transcription factors, of which NAC factor ORE1 (ANAC092) is crucial in Arabidopsis thaliana. Enhanced expression of ORE1 triggers early senescence by controlling a downstream gene network that includes various senescence-associated genes. Here, we report that unexpectedly ORE1 interacts with the G2-like transcription factors GLK1 and GLK2, which are important for chloroplast development and maintenance, and thereby for leaf maintenance. ORE1 antagonizes GLK transcriptional activity, shifting the balance from chloroplast maintenance towards deterioration. Our finding identifies a new mechanism important for the control of senescence by ORE1.

Original language	English
Pages (from-to)	382-388
Number of pages	7
Journal	EMBO Reports
Volume	14
Issue number	4
DOIs	https://doi.org/10.1038/embor.2013.24
State	Published - Apr 2013

Keywords

chloroplast
proteinprotein interaction
senescence
transcription factor

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10.1038/embor.2013.24

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title = "ORE1 balances leaf senescence against maintenance by antagonizing G2-like-mediated transcription",

abstract = "Leaf senescence is a key physiological process in all plants. Its onset is tightly controlled by transcription factors, of which NAC factor ORE1 (ANAC092) is crucial in Arabidopsis thaliana. Enhanced expression of ORE1 triggers early senescence by controlling a downstream gene network that includes various senescence-associated genes. Here, we report that unexpectedly ORE1 interacts with the G2-like transcription factors GLK1 and GLK2, which are important for chloroplast development and maintenance, and thereby for leaf maintenance. ORE1 antagonizes GLK transcriptional activity, shifting the balance from chloroplast maintenance towards deterioration. Our finding identifies a new mechanism important for the control of senescence by ORE1.",

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language = "English",

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T1 - ORE1 balances leaf senescence against maintenance by antagonizing G2-like-mediated transcription

AU - Rauf, Mamoona

AU - Arif, Muhammad

AU - Dortay, Hakan

AU - Matallana-Ramírez, Lilian P.

AU - Waters, Mark T.

AU - Gil Nam, Hong

AU - Lim, Pyung Ok

AU - Mueller-Roeber, Bernd

AU - Balazadeh, Salma

PY - 2013/4

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N2 - Leaf senescence is a key physiological process in all plants. Its onset is tightly controlled by transcription factors, of which NAC factor ORE1 (ANAC092) is crucial in Arabidopsis thaliana. Enhanced expression of ORE1 triggers early senescence by controlling a downstream gene network that includes various senescence-associated genes. Here, we report that unexpectedly ORE1 interacts with the G2-like transcription factors GLK1 and GLK2, which are important for chloroplast development and maintenance, and thereby for leaf maintenance. ORE1 antagonizes GLK transcriptional activity, shifting the balance from chloroplast maintenance towards deterioration. Our finding identifies a new mechanism important for the control of senescence by ORE1.

AB - Leaf senescence is a key physiological process in all plants. Its onset is tightly controlled by transcription factors, of which NAC factor ORE1 (ANAC092) is crucial in Arabidopsis thaliana. Enhanced expression of ORE1 triggers early senescence by controlling a downstream gene network that includes various senescence-associated genes. Here, we report that unexpectedly ORE1 interacts with the G2-like transcription factors GLK1 and GLK2, which are important for chloroplast development and maintenance, and thereby for leaf maintenance. ORE1 antagonizes GLK transcriptional activity, shifting the balance from chloroplast maintenance towards deterioration. Our finding identifies a new mechanism important for the control of senescence by ORE1.

KW - chloroplast

KW - proteinprotein interaction

KW - senescence

KW - transcription factor

UR - https://www.scopus.com/pages/publications/84876474849

U2 - 10.1038/embor.2013.24

DO - 10.1038/embor.2013.24

M3 - Article

C2 - 23459204

AN - SCOPUS:84876474849

SN - 1469-221X

VL - 14

SP - 382

EP - 388

JO - EMBO Reports

JF - EMBO Reports

IS - 4

ER -

ORE1 balances leaf senescence against maintenance by antagonizing G2-like-mediated transcription

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Keywords

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