Optimal sound speed estimation to enhance photo acoustic image quality in breast microcalcification detection

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

Photoacoustic imaging (PAI) based on an array transducer involves a delay-and-sum beamforming (DAS-BF) method using an assumed fixed sound speed, e.g., 1540 m/s. However, true sound speed in soft tissues varies approximately 1450 m/s to 1600 m/s, leading to degradation of the PAI quality. In this paper, a method for estimating an optimal sound speed is proposed to enhance the quality of cross-sectional PAI. In the method, the modified nonlinear anisotropic diffusion (MNAD) is utilized to reduce the artifacts stemming from the defocusing of ultrasound waves and quality of PAI is quantified using the edge conspicuity (EC). In addition, a standard optimization method (e.g., golden section search) is employed for real-time operation of the proposed method. The performances of the method were evaluated with ex vivo experiments. The results demonstrated that improvement of PA image quality can be achieved when the optimal sound speed estimated by the proposed method is utilized.

Original languageEnglish
Title of host publicationProceedings of the IASTED International Conference on Signal and Image Processing, SIP 2012
Pages228-234
Number of pages7
DOIs
StatePublished - 2012
Event14th IASTED International Conference on Signal and Image Processing, SIP 2012 - Honolulu, HI, United States
Duration: 20 Aug 201222 Aug 2012

Publication series

NameProceedings of the IASTED International Conference on Signal and Image Processing, SIP 2012

Conference

Conference14th IASTED International Conference on Signal and Image Processing, SIP 2012
Country/TerritoryUnited States
CityHonolulu, HI
Period20/08/1222/08/12

Keywords

  • Beamforming
  • Microcalcification
  • Nonlinear anisotropic diffusion
  • Photoacoustic imaging
  • Sound speed estimation

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