Nanomaterials and continuous wave laser-based efficient desorption for atmospheric pressure mass spectrometric imaging of live hippocampal tissue slices

Jae Young Kim; Eun Seok Seo; Hee Jin Lim; Hyunmin Kim; Ji Won Park; Hyeon Ho Shin; Dong Kwon Lim; Dae Won Moon

doi:10.1039/c8ra00038g

Nanomaterials and continuous wave laser-based efficient desorption for atmospheric pressure mass spectrometric imaging of live hippocampal tissue slices

Jae Young Kim, Eun Seok Seo, Hee Jin Lim, Hyunmin Kim, Ji Won Park, Hyeon Ho Shin, Dong Kwon Lim, Dae Won Moon

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Abstract

Micrometer-resolution mass spectrometric imaging of live hippocampal tissue is achieved with a highly efficient desorption of biomolecules using a 532 nm continuous wave laser and gold nanoparticles or graphene oxide as an energy transporter, which enables clear identification of the distributions of monoacylglycerol, adenine, cholesterol, sphingosine and ceramide.

Original language	English
Pages (from-to)	8021-8025
Number of pages	5
Journal	RSC Advances
Volume	8
Issue number	15
DOIs	https://doi.org/10.1039/c8ra00038g
State	Published - 2018

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© The Royal Society of Chemistry 2018.

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title = "Nanomaterials and continuous wave laser-based efficient desorption for atmospheric pressure mass spectrometric imaging of live hippocampal tissue slices",

abstract = "Micrometer-resolution mass spectrometric imaging of live hippocampal tissue is achieved with a highly efficient desorption of biomolecules using a 532 nm continuous wave laser and gold nanoparticles or graphene oxide as an energy transporter, which enables clear identification of the distributions of monoacylglycerol, adenine, cholesterol, sphingosine and ceramide.",

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AU - Kim, Jae Young

AU - Seo, Eun Seok

AU - Lim, Hee Jin

AU - Kim, Hyunmin

AU - Park, Ji Won

AU - Shin, Hyeon Ho

AU - Lim, Dong Kwon

AU - Moon, Dae Won

PY - 2018

Y1 - 2018

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AB - Micrometer-resolution mass spectrometric imaging of live hippocampal tissue is achieved with a highly efficient desorption of biomolecules using a 532 nm continuous wave laser and gold nanoparticles or graphene oxide as an energy transporter, which enables clear identification of the distributions of monoacylglycerol, adenine, cholesterol, sphingosine and ceramide.

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DO - 10.1039/c8ra00038g

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VL - 8

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EP - 8025

JO - RSC Advances

JF - RSC Advances

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ER -

Nanomaterials and continuous wave laser-based efficient desorption for atmospheric pressure mass spectrometric imaging of live hippocampal tissue slices

Abstract

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