Microphysiological network and coculture of five micro organs (cortical and hippocampal brain, cardiac, liver, and tumor 3D microtissues) on 96Well format based body on a chip

Chaewon Jin; Hongsoo Choi; Jinyoung Kim

Microphysiological network and coculture of five micro organs (cortical and hippocampal brain, cardiac, liver, and tumor 3D microtissues) on 96Well format based body on a chip

Chaewon Jin
, Hongsoo Choi
, Jinyoung Kim

Daegu Gyeongbuk Institute of Science and Technology

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

Abstract

In this study, an in-vitro microphysiological network of five different micro-organs has been established on a 96-well format-based microfluidic device to realize the body-on-a-chip. Five types of 3D organotypic microtissues (MTs); Cortical neuronal (CN), Hippocampal neuronal (HN) brain (Br), Cardiac (Cd), Liver (Li) and Tumor (Tm) MTs, were fluidically interconnected and co-cultured in the device over 8 days in order to mimic cortexhippocampus-heart-liver-tumor network in-vitro.

Original language	English
Title of host publication	23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019
Publisher	Chemical and Biological Microsystems Society
Pages	380-381
Number of pages	2
ISBN (Electronic)	9781733419000
State	Published - 2019
Event	23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019 - Basel, Switzerland Duration: 27 Oct 2019 → 31 Oct 2019

Publication series

Name	23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019

Conference

Conference	23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019
Country/Territory	Switzerland
City	Basel
Period	27/10/19 → 31/10/19

Bibliographical note

Publisher Copyright:
© 2019 CBMS-0001.

Keywords

3D cell culture
Co-culture
In-vitro micro-organ network
Microfluidics
Microtissue

Cite this

Jin, C., Choi, H., & Kim, J. (2019). Microphysiological network and coculture of five micro organs (cortical and hippocampal brain, cardiac, liver, and tumor 3D microtissues) on 96Well format based body on a chip. In 23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019 (pp. 380-381). (23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019). Chemical and Biological Microsystems Society.

Jin, Chaewon ; Choi, Hongsoo ; Kim, Jinyoung. / Microphysiological network and coculture of five micro organs (cortical and hippocampal brain, cardiac, liver, and tumor 3D microtissues) on 96Well format based body on a chip. 23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019. Chemical and Biological Microsystems Society, 2019. pp. 380-381 (23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019).

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title = "Microphysiological network and coculture of five micro organs (cortical and hippocampal brain, cardiac, liver, and tumor 3D microtissues) on 96Well format based body on a chip",

abstract = "In this study, an in-vitro microphysiological network of five different micro-organs has been established on a 96-well format-based microfluidic device to realize the body-on-a-chip. Five types of 3D organotypic microtissues (MTs); Cortical neuronal (CN), Hippocampal neuronal (HN) brain (Br), Cardiac (Cd), Liver (Li) and Tumor (Tm) MTs, were fluidically interconnected and co-cultured in the device over 8 days in order to mimic cortexhippocampus-heart-liver-tumor network in-vitro.",

keywords = "3D cell culture, Co-culture, In-vitro micro-organ network, Microfluidics, Microtissue",

author = "Chaewon Jin and Hongsoo Choi and Jinyoung Kim",

note = "Publisher Copyright: {\textcopyright} 2019 CBMS-0001.; 23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019 ; Conference date: 27-10-2019 Through 31-10-2019",

year = "2019",

language = "English",

series = "23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019",

publisher = "Chemical and Biological Microsystems Society",

pages = "380--381",

booktitle = "23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019",

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Jin, C, Choi, H & Kim, J 2019, Microphysiological network and coculture of five micro organs (cortical and hippocampal brain, cardiac, liver, and tumor 3D microtissues) on 96Well format based body on a chip. in 23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019. 23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019, Chemical and Biological Microsystems Society, pp. 380-381, 23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019, Basel, Switzerland, 27/10/19.

Microphysiological network and coculture of five micro organs (cortical and hippocampal brain, cardiac, liver, and tumor 3D microtissues) on 96Well format based body on a chip. / Jin, Chaewon; Choi, Hongsoo ; Kim, Jinyoung.
23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019. Chemical and Biological Microsystems Society, 2019. p. 380-381 (23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

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AU - Kim, Jinyoung

PY - 2019

Y1 - 2019

N2 - In this study, an in-vitro microphysiological network of five different micro-organs has been established on a 96-well format-based microfluidic device to realize the body-on-a-chip. Five types of 3D organotypic microtissues (MTs); Cortical neuronal (CN), Hippocampal neuronal (HN) brain (Br), Cardiac (Cd), Liver (Li) and Tumor (Tm) MTs, were fluidically interconnected and co-cultured in the device over 8 days in order to mimic cortexhippocampus-heart-liver-tumor network in-vitro.

AB - In this study, an in-vitro microphysiological network of five different micro-organs has been established on a 96-well format-based microfluidic device to realize the body-on-a-chip. Five types of 3D organotypic microtissues (MTs); Cortical neuronal (CN), Hippocampal neuronal (HN) brain (Br), Cardiac (Cd), Liver (Li) and Tumor (Tm) MTs, were fluidically interconnected and co-cultured in the device over 8 days in order to mimic cortexhippocampus-heart-liver-tumor network in-vitro.

KW - 3D cell culture

KW - Co-culture

KW - In-vitro micro-organ network

KW - Microfluidics

KW - Microtissue

UR - https://www.scopus.com/pages/publications/85094979662

M3 - Conference contribution

AN - SCOPUS:85094979662

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SP - 380

EP - 381

BT - 23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019

PB - Chemical and Biological Microsystems Society

T2 - 23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019

Y2 - 27 October 2019 through 31 October 2019

ER -

Jin C, Choi H , Kim J. Microphysiological network and coculture of five micro organs (cortical and hippocampal brain, cardiac, liver, and tumor 3D microtissues) on 96Well format based body on a chip. In 23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019. Chemical and Biological Microsystems Society. 2019. p. 380-381. (23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019).

Microphysiological network and coculture of five micro organs (cortical and hippocampal brain, cardiac, liver, and tumor 3D microtissues) on 96Well format based body on a chip

Abstract

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Conference

Bibliographical note

Keywords

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Cite this