Microarray analysis of piceatannol-induced changes in gene expression in human gastric cancer cells

Dooil Jeoung; Seong Jun Oh; Seongeun Lee; Myungin Baek; Youn Hyung Lee; Nam In Baek; Hae Yeong Kim

doi:10.1023/A:1014517515785

Microarray analysis of piceatannol-induced changes in gene expression in human gastric cancer cells

Dooil Jeoung
, Seong Jun Oh
, Seongeun Lee
, Myungin Baek
, Youn Hyung Lee
, Nam In Baek
, Hae Yeong Kim

Department of Brain Sciences

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Abstract

Piceatannol, isolated from the roots of Rheum undulatum, prevented oxygen radical formation and inhibited lipid peroxidation; the effective concentrations were 25/μM for a radical scavenging assay and 2.1/μM for a microsome assay. Using cDNA microarray analysis to determine which genes were modulated by piceatannol, 33 genes were up-regulated while 157 genes were down-regulated in the human gastric cancer cell line.

Original language	English
Pages (from-to)	463-467
Number of pages	5
Journal	Biotechnology Letters
Volume	24
Issue number	6
DOIs	https://doi.org/10.1023/A:1014517515785
State	Published - 2002

Keywords

Antioxidant
Microarray
Piceatannol
RT-PCR
Rheum undulatum L.

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1023/A:1014517515785

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title = "Microarray analysis of piceatannol-induced changes in gene expression in human gastric cancer cells",

abstract = "Piceatannol, isolated from the roots of Rheum undulatum, prevented oxygen radical formation and inhibited lipid peroxidation; the effective concentrations were 25/μM for a radical scavenging assay and 2.1/μM for a microsome assay. Using cDNA microarray analysis to determine which genes were modulated by piceatannol, 33 genes were up-regulated while 157 genes were down-regulated in the human gastric cancer cell line.",

keywords = "Antioxidant, Microarray, Piceatannol, RT-PCR, Rheum undulatum L.",

author = "Dooil Jeoung and Oh, \{Seong Jun\} and Seongeun Lee and Myungin Baek and Lee, \{Youn Hyung\} and Baek, \{Nam In\} and Kim, \{Hae Yeong\}",

year = "2002",

doi = "10.1023/A:1014517515785",

language = "English",

volume = "24",

pages = "463--467",

journal = "Biotechnology Letters",

issn = "0141-5492",

publisher = "Springer Science and Business Media B.V.",

number = "6",

}

TY - JOUR

T1 - Microarray analysis of piceatannol-induced changes in gene expression in human gastric cancer cells

AU - Jeoung, Dooil

AU - Oh, Seong Jun

AU - Lee, Seongeun

AU - Baek, Myungin

AU - Lee, Youn Hyung

AU - Baek, Nam In

AU - Kim, Hae Yeong

PY - 2002

Y1 - 2002

N2 - Piceatannol, isolated from the roots of Rheum undulatum, prevented oxygen radical formation and inhibited lipid peroxidation; the effective concentrations were 25/μM for a radical scavenging assay and 2.1/μM for a microsome assay. Using cDNA microarray analysis to determine which genes were modulated by piceatannol, 33 genes were up-regulated while 157 genes were down-regulated in the human gastric cancer cell line.

AB - Piceatannol, isolated from the roots of Rheum undulatum, prevented oxygen radical formation and inhibited lipid peroxidation; the effective concentrations were 25/μM for a radical scavenging assay and 2.1/μM for a microsome assay. Using cDNA microarray analysis to determine which genes were modulated by piceatannol, 33 genes were up-regulated while 157 genes were down-regulated in the human gastric cancer cell line.

KW - Antioxidant

KW - Microarray

KW - Piceatannol

KW - RT-PCR

KW - Rheum undulatum L.

UR - https://www.scopus.com/pages/publications/0036206588

U2 - 10.1023/A:1014517515785

DO - 10.1023/A:1014517515785

M3 - Article

AN - SCOPUS:0036206588

SN - 0141-5492

VL - 24

SP - 463

EP - 467

JO - Biotechnology Letters

JF - Biotechnology Letters

IS - 6

ER -

Microarray analysis of piceatannol-induced changes in gene expression in human gastric cancer cells

Abstract

Keywords

UN SDGs

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