Microarray analysis of piceatannol-induced changes in gene expression in human gastric cancer cells

Dooil Jeoung; Seong Jun Oh; Seongeun Lee; Myungin Baek; Youn Hyung Lee; Nam In Baek; Hae Yeong Kim

doi:10.1023/A:1014517515785

Microarray analysis of piceatannol-induced changes in gene expression in human gastric cancer cells

Dooil Jeoung, Seong Jun Oh, Seongeun Lee, Myungin Baek, Youn Hyung Lee, Nam In Baek, Hae Yeong Kim

Department of Brain Sciences

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Abstract

Piceatannol, isolated from the roots of Rheum undulatum, prevented oxygen radical formation and inhibited lipid peroxidation; the effective concentrations were 25/μM for a radical scavenging assay and 2.1/μM for a microsome assay. Using cDNA microarray analysis to determine which genes were modulated by piceatannol, 33 genes were up-regulated while 157 genes were down-regulated in the human gastric cancer cell line.

Original language	English
Pages (from-to)	463-467
Number of pages	5
Journal	Biotechnology Letters
Volume	24
Issue number	6
DOIs	https://doi.org/10.1023/A:1014517515785
State	Published - 2002

Keywords

Antioxidant
Microarray
Piceatannol
RT-PCR
Rheum undulatum L.

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This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1023/A:1014517515785

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title = "Microarray analysis of piceatannol-induced changes in gene expression in human gastric cancer cells",

abstract = "Piceatannol, isolated from the roots of Rheum undulatum, prevented oxygen radical formation and inhibited lipid peroxidation; the effective concentrations were 25/μM for a radical scavenging assay and 2.1/μM for a microsome assay. Using cDNA microarray analysis to determine which genes were modulated by piceatannol, 33 genes were up-regulated while 157 genes were down-regulated in the human gastric cancer cell line.",

keywords = "Antioxidant, Microarray, Piceatannol, RT-PCR, Rheum undulatum L.",

author = "Dooil Jeoung and Oh, {Seong Jun} and Seongeun Lee and Myungin Baek and Lee, {Youn Hyung} and Baek, {Nam In} and Kim, {Hae Yeong}",

year = "2002",

doi = "10.1023/A:1014517515785",

language = "English",

volume = "24",

pages = "463--467",

journal = "Biotechnology Letters",

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TY - JOUR

T1 - Microarray analysis of piceatannol-induced changes in gene expression in human gastric cancer cells

AU - Jeoung, Dooil

AU - Oh, Seong Jun

AU - Lee, Seongeun

AU - Baek, Myungin

AU - Lee, Youn Hyung

AU - Baek, Nam In

AU - Kim, Hae Yeong

PY - 2002

Y1 - 2002

N2 - Piceatannol, isolated from the roots of Rheum undulatum, prevented oxygen radical formation and inhibited lipid peroxidation; the effective concentrations were 25/μM for a radical scavenging assay and 2.1/μM for a microsome assay. Using cDNA microarray analysis to determine which genes were modulated by piceatannol, 33 genes were up-regulated while 157 genes were down-regulated in the human gastric cancer cell line.

AB - Piceatannol, isolated from the roots of Rheum undulatum, prevented oxygen radical formation and inhibited lipid peroxidation; the effective concentrations were 25/μM for a radical scavenging assay and 2.1/μM for a microsome assay. Using cDNA microarray analysis to determine which genes were modulated by piceatannol, 33 genes were up-regulated while 157 genes were down-regulated in the human gastric cancer cell line.

KW - Antioxidant

KW - Microarray

KW - Piceatannol

KW - RT-PCR

KW - Rheum undulatum L.

UR - http://www.scopus.com/inward/record.url?scp=0036206588&partnerID=8YFLogxK

U2 - 10.1023/A:1014517515785

DO - 10.1023/A:1014517515785

M3 - Article

AN - SCOPUS:0036206588

SN - 0141-5492

VL - 24

SP - 463

EP - 467

JO - Biotechnology Letters

JF - Biotechnology Letters

IS - 6

ER -

Microarray analysis of piceatannol-induced changes in gene expression in human gastric cancer cells

Abstract

Keywords

UN SDGs

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