Abstract
Leucine-rich repeats (LRRs) are 20-29-aa motifs that mediate protein-protein interactions and are present in a variety of membrane and cytoplasmic proteins. Many LRR proteins with neuronal functions have been reported. Here, we summarize an emerging group of synaptic LRR proteins, which includes densin-180, Erbin, NGL, SALM, and LGI1. These proteins have been implicated in the formation, differentiation, maintenance, and plasticity of neuronal synapses.
| Original language | English |
|---|---|
| Pages (from-to) | 2824-2832 |
| Number of pages | 9 |
| Journal | Journal of Neuroscience Research |
| Volume | 85 |
| Issue number | 13 |
| DOIs | |
| State | Published - Oct 2007 |
Keywords
- Cell adhesion molecule
- Densin-180
- Erbin
- LGI1
- LRR
- NGL
- SALM