Abstract
Leucine-rich repeats (LRRs) are 20-29-aa motifs that mediate protein-protein interactions and are present in a variety of membrane and cytoplasmic proteins. Many LRR proteins with neuronal functions have been reported. Here, we summarize an emerging group of synaptic LRR proteins, which includes densin-180, Erbin, NGL, SALM, and LGI1. These proteins have been implicated in the formation, differentiation, maintenance, and plasticity of neuronal synapses.
Original language | English |
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Pages (from-to) | 2824-2832 |
Number of pages | 9 |
Journal | Journal of Neuroscience Research |
Volume | 85 |
Issue number | 13 |
DOIs | |
State | Published - Oct 2007 |
Keywords
- Cell adhesion molecule
- Densin-180
- Erbin
- LGI1
- LRR
- NGL
- SALM