False dyssynchrony: Problem with image-based cardiac functional analysis using x-ray computed tomography

Masafumi Kidoh; Zeyang Shen; Yuki Suzuki; Luisa Ciuffo; Hiroshi Ashikaga; George S.K. Fung; Yoshito Otake; Stefan L. Zimmerman; Joao A.C. Lima; Takahiro Higuchi; Okkyun Lee; Yoshinobu Sato; Lewis C. Becker; Elliot K. Fishman; Katsuyuki Taguchi

doi:10.1117/12.2250257

False dyssynchrony: Problem with image-based cardiac functional analysis using x-ray computed tomography

Masafumi Kidoh, Zeyang Shen, Yuki Suzuki, Luisa Ciuffo, Hiroshi Ashikaga, George S.K. Fung, Yoshito Otake, Stefan L. Zimmerman, Joao A.C. Lima, Takahiro Higuchi, Okkyun Lee, Yoshinobu Sato, Lewis C. Becker, Elliot K. Fishman, Katsuyuki Taguchi

Department of Robotics and Mechatronics Engineering

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

5 Scopus citations

Abstract

We have developed a digitally synthesized patient which we call "Zach" (Zero millisecond Adjustable Clinical Heart) phantom, which allows for an access to the ground truth and assessment of image-based cardiac functional analysis (CFA) using CT images with clinically realistic settings. The study using Zach phantom revealed a major problem with image-based CFA: "False dyssynchrony." Even though the true motion of wall segments is in synchrony, it may appear to be dyssynchrony with the reconstructed cardiac CT images. It is attributed to how cardiac images are reconstructed and how wall locations are updated over cardiac phases. The presence and the degree of false dyssynchrony may vary from scan-to-scan, which could degrade the accuracy and the repeatability (or precision) of image-based CT-CFA exams.

Original language	English
Title of host publication	Medical Imaging 2017
Subtitle of host publication	Physics of Medical Imaging
Editors	Taly Gilat Schmidt, Joseph Y. Lo, Thomas G. Flohr
Publisher	SPIE
ISBN (Electronic)	9781510607095
DOIs	https://doi.org/10.1117/12.2250257
State	Published - 2017
Event	Medical Imaging 2017: Physics of Medical Imaging - Orlando, United States Duration: 13 Feb 2017 → 16 Feb 2017

Publication series

Name	Progress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume	10132
ISSN (Print)	1605-7422

Conference

Conference	Medical Imaging 2017: Physics of Medical Imaging
Country/Territory	United States
City	Orlando
Period	13/02/17 → 16/02/17

Bibliographical note

Publisher Copyright:
© 2017 SPIE.

Keywords

Cardiac function analysis
Computed tomography
Dyssynchrony

Access to Document

10.1117/12.2250257

Cite this

Kidoh, M., Shen, Z., Suzuki, Y., Ciuffo, L., Ashikaga, H., Fung, G. S. K., Otake, Y., Zimmerman, S. L., Lima, J. A. C., Higuchi, T., Lee, O., Sato, Y., Becker, L. C., Fishman, E. K., & Taguchi, K. (2017). False dyssynchrony: Problem with image-based cardiac functional analysis using x-ray computed tomography. In T. G. Schmidt, J. Y. Lo, & T. G. Flohr (Eds.), Medical Imaging 2017: Physics of Medical Imaging Article 101321U (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 10132). SPIE. https://doi.org/10.1117/12.2250257

@inproceedings{4b943e8ad9334d2daaa1b249bed1980d,

title = "False dyssynchrony: Problem with image-based cardiac functional analysis using x-ray computed tomography",

abstract = "We have developed a digitally synthesized patient which we call {"}Zach{"} (Zero millisecond Adjustable Clinical Heart) phantom, which allows for an access to the ground truth and assessment of image-based cardiac functional analysis (CFA) using CT images with clinically realistic settings. The study using Zach phantom revealed a major problem with image-based CFA: {"}False dyssynchrony.{"} Even though the true motion of wall segments is in synchrony, it may appear to be dyssynchrony with the reconstructed cardiac CT images. It is attributed to how cardiac images are reconstructed and how wall locations are updated over cardiac phases. The presence and the degree of false dyssynchrony may vary from scan-to-scan, which could degrade the accuracy and the repeatability (or precision) of image-based CT-CFA exams.",

keywords = "Cardiac function analysis, Computed tomography, Dyssynchrony",

author = "Masafumi Kidoh and Zeyang Shen and Yuki Suzuki and Luisa Ciuffo and Hiroshi Ashikaga and Fung, \{George S.K.\} and Yoshito Otake and Zimmerman, \{Stefan L.\} and Lima, \{Joao A.C.\} and Takahiro Higuchi and Okkyun Lee and Yoshinobu Sato and Becker, \{Lewis C.\} and Fishman, \{Elliot K.\} and Katsuyuki Taguchi",

note = "Publisher Copyright: {\textcopyright} 2017 SPIE.; Medical Imaging 2017: Physics of Medical Imaging ; Conference date: 13-02-2017 Through 16-02-2017",

year = "2017",

doi = "10.1117/12.2250257",

language = "English",

series = "Progress in Biomedical Optics and Imaging - Proceedings of SPIE",

publisher = "SPIE",

editor = "Schmidt, \{Taly Gilat\} and Lo, \{Joseph Y.\} and Flohr, \{Thomas G.\}",

booktitle = "Medical Imaging 2017",

}

Kidoh, M, Shen, Z, Suzuki, Y, Ciuffo, L, Ashikaga, H, Fung, GSK, Otake, Y, Zimmerman, SL, Lima, JAC, Higuchi, T, Lee, O, Sato, Y, Becker, LC, Fishman, EK & Taguchi, K 2017, False dyssynchrony: Problem with image-based cardiac functional analysis using x-ray computed tomography. in TG Schmidt, JY Lo & TG Flohr (eds), Medical Imaging 2017: Physics of Medical Imaging., 101321U, Progress in Biomedical Optics and Imaging - Proceedings of SPIE, vol. 10132, SPIE, Medical Imaging 2017: Physics of Medical Imaging, Orlando, United States, 13/02/17. https://doi.org/10.1117/12.2250257

False dyssynchrony: Problem with image-based cardiac functional analysis using x-ray computed tomography. / Kidoh, Masafumi; Shen, Zeyang; Suzuki, Yuki et al.
Medical Imaging 2017: Physics of Medical Imaging. ed. / Taly Gilat Schmidt; Joseph Y. Lo; Thomas G. Flohr. SPIE, 2017. 101321U (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 10132).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

TY - GEN

T1 - False dyssynchrony

T2 - Medical Imaging 2017: Physics of Medical Imaging

AU - Kidoh, Masafumi

AU - Shen, Zeyang

AU - Suzuki, Yuki

AU - Ciuffo, Luisa

AU - Ashikaga, Hiroshi

AU - Fung, George S.K.

AU - Otake, Yoshito

AU - Zimmerman, Stefan L.

AU - Lima, Joao A.C.

AU - Higuchi, Takahiro

AU - Lee, Okkyun

AU - Sato, Yoshinobu

AU - Becker, Lewis C.

AU - Fishman, Elliot K.

AU - Taguchi, Katsuyuki

PY - 2017

Y1 - 2017

N2 - We have developed a digitally synthesized patient which we call "Zach" (Zero millisecond Adjustable Clinical Heart) phantom, which allows for an access to the ground truth and assessment of image-based cardiac functional analysis (CFA) using CT images with clinically realistic settings. The study using Zach phantom revealed a major problem with image-based CFA: "False dyssynchrony." Even though the true motion of wall segments is in synchrony, it may appear to be dyssynchrony with the reconstructed cardiac CT images. It is attributed to how cardiac images are reconstructed and how wall locations are updated over cardiac phases. The presence and the degree of false dyssynchrony may vary from scan-to-scan, which could degrade the accuracy and the repeatability (or precision) of image-based CT-CFA exams.

AB - We have developed a digitally synthesized patient which we call "Zach" (Zero millisecond Adjustable Clinical Heart) phantom, which allows for an access to the ground truth and assessment of image-based cardiac functional analysis (CFA) using CT images with clinically realistic settings. The study using Zach phantom revealed a major problem with image-based CFA: "False dyssynchrony." Even though the true motion of wall segments is in synchrony, it may appear to be dyssynchrony with the reconstructed cardiac CT images. It is attributed to how cardiac images are reconstructed and how wall locations are updated over cardiac phases. The presence and the degree of false dyssynchrony may vary from scan-to-scan, which could degrade the accuracy and the repeatability (or precision) of image-based CT-CFA exams.

KW - Cardiac function analysis

KW - Computed tomography

KW - Dyssynchrony

UR - https://www.scopus.com/pages/publications/85020477614

U2 - 10.1117/12.2250257

DO - 10.1117/12.2250257

M3 - Conference contribution

AN - SCOPUS:85020477614

T3 - Progress in Biomedical Optics and Imaging - Proceedings of SPIE

BT - Medical Imaging 2017

A2 - Schmidt, Taly Gilat

A2 - Lo, Joseph Y.

A2 - Flohr, Thomas G.

PB - SPIE

Y2 - 13 February 2017 through 16 February 2017

ER -

Kidoh M, Shen Z, Suzuki Y, Ciuffo L, Ashikaga H, Fung GSK et al. False dyssynchrony: Problem with image-based cardiac functional analysis using x-ray computed tomography. In Schmidt TG, Lo JY, Flohr TG, editors, Medical Imaging 2017: Physics of Medical Imaging. SPIE. 2017. 101321U. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE). doi: 10.1117/12.2250257

False dyssynchrony: Problem with image-based cardiac functional analysis using x-ray computed tomography

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Keywords

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