Fabrication of N-isopropylacrylamide (NIPAAM) based micro-hydrogel using UV LED microscope

Ho Lee; Seong Young Ko; Jong Oh Park; Dongshin Kim; Sathish Akella; Ye Zhang; Seth Fraden; Sukho Park

doi:10.1109/ICCAS.2014.6988018

Fabrication of N-isopropylacrylamide (NIPAAM) based micro-hydrogel using UV LED microscope

Ho Lee
, Seong Young Ko
, Jong Oh Park
, Dongshin Kim
, Sathish Akella
, Ye Zhang
, Seth Fraden
, Sukho Park

Department of Robotics and Mechatronics Engineering

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

1 Scopus citations

Abstract

Poly-N-isopropylacrylamide (poly-NIPAAM) has been widely used in tissue engineering and micro-structure in micro-fluidic applications. Generally, NIPAAM is polymerized and patterned by a conventional UV irradiation or UV lithography. This paper proposes a photo-polymerization method of NIPAAM using UV LED microscope. Through the combination of a commercialized UV LED, optical components, an objective lens and X-Y-Z motorized stage, we fabricated a UV LED microscope for the photo-polymerization of NIPAAM. In addition, for the investigation of the polymerization procedure, CCD camera and an illumination light source using red LED and optical components were installed. For the polymerization of NIPAAM solution, a simple micro-fluidic channel was fabricated and the NIPAAM base solution was injected into the micro-fluidic channel. If the UV LED beam was focused on the channel with NIPAAM solution, the NIPAAM can be polymerized in the focused region. Finally, we can directly fabricate micro-structures of poly-NIPAAM by using the proposed UV LED microscope.

Original language	English
Title of host publication	International Conference on Control, Automation and Systems
Publisher	IEEE Computer Society
Pages	342-344
Number of pages	3
ISBN (Electronic)	9788993215069
DOIs	https://doi.org/10.1109/ICCAS.2014.6988018
State	Published - 16 Dec 2014
Event	2014 14th International Conference on Control, Automation and Systems, ICCAS 2014 - Gyeonggi-do, Korea, Republic of Duration: 22 Oct 2014 → 25 Oct 2014

Publication series

Name	International Conference on Control, Automation and Systems
ISSN (Print)	1598-7833

Conference

Conference	2014 14th International Conference on Control, Automation and Systems, ICCAS 2014
Country/Territory	Korea, Republic of
City	Gyeonggi-do
Period	22/10/14 → 25/10/14

Bibliographical note

Publisher Copyright:
© 2014 Institute of Control, Robotics and Systems (ICROS).

Keywords

LED microscope
Micropatterning
Photopolymerization
Poly-N-isopropylacrylamide (poly-NIPAAM)
UV lithography

Access to Document

10.1109/ICCAS.2014.6988018

Cite this

Lee, H., Ko, S. Y., Park, J. O., Kim, D., Akella, S., Zhang, Y., Fraden, S., & Park, S. (2014). Fabrication of N-isopropylacrylamide (NIPAAM) based micro-hydrogel using UV LED microscope. In International Conference on Control, Automation and Systems (pp. 342-344). Article 6988018 (International Conference on Control, Automation and Systems). IEEE Computer Society. https://doi.org/10.1109/ICCAS.2014.6988018

@inproceedings{d9a8223944cf4a3b821078523b57fa18,

title = "Fabrication of N-isopropylacrylamide (NIPAAM) based micro-hydrogel using UV LED microscope",

abstract = "Poly-N-isopropylacrylamide (poly-NIPAAM) has been widely used in tissue engineering and micro-structure in micro-fluidic applications. Generally, NIPAAM is polymerized and patterned by a conventional UV irradiation or UV lithography. This paper proposes a photo-polymerization method of NIPAAM using UV LED microscope. Through the combination of a commercialized UV LED, optical components, an objective lens and X-Y-Z motorized stage, we fabricated a UV LED microscope for the photo-polymerization of NIPAAM. In addition, for the investigation of the polymerization procedure, CCD camera and an illumination light source using red LED and optical components were installed. For the polymerization of NIPAAM solution, a simple micro-fluidic channel was fabricated and the NIPAAM base solution was injected into the micro-fluidic channel. If the UV LED beam was focused on the channel with NIPAAM solution, the NIPAAM can be polymerized in the focused region. Finally, we can directly fabricate micro-structures of poly-NIPAAM by using the proposed UV LED microscope.",

keywords = "LED microscope, Micropatterning, Photopolymerization, Poly-N-isopropylacrylamide (poly-NIPAAM), UV lithography",

author = "Ho Lee and Ko, \{Seong Young\} and Park, \{Jong Oh\} and Dongshin Kim and Sathish Akella and Ye Zhang and Seth Fraden and Sukho Park",

note = "Publisher Copyright: {\textcopyright} 2014 Institute of Control, Robotics and Systems (ICROS).; 2014 14th International Conference on Control, Automation and Systems, ICCAS 2014 ; Conference date: 22-10-2014 Through 25-10-2014",

year = "2014",

month = dec,

day = "16",

doi = "10.1109/ICCAS.2014.6988018",

language = "English",

series = "International Conference on Control, Automation and Systems",

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Lee, H, Ko, SY, Park, JO, Kim, D, Akella, S, Zhang, Y, Fraden, S & Park, S 2014, Fabrication of N-isopropylacrylamide (NIPAAM) based micro-hydrogel using UV LED microscope. in International Conference on Control, Automation and Systems., 6988018, International Conference on Control, Automation and Systems, IEEE Computer Society, pp. 342-344, 2014 14th International Conference on Control, Automation and Systems, ICCAS 2014, Gyeonggi-do, Korea, Republic of, 22/10/14. https://doi.org/10.1109/ICCAS.2014.6988018

Fabrication of N-isopropylacrylamide (NIPAAM) based micro-hydrogel using UV LED microscope. / Lee, Ho; Ko, Seong Young; Park, Jong Oh et al.
International Conference on Control, Automation and Systems. IEEE Computer Society, 2014. p. 342-344 6988018 (International Conference on Control, Automation and Systems).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

TY - GEN

T1 - Fabrication of N-isopropylacrylamide (NIPAAM) based micro-hydrogel using UV LED microscope

AU - Lee, Ho

AU - Ko, Seong Young

AU - Park, Jong Oh

AU - Kim, Dongshin

AU - Akella, Sathish

AU - Zhang, Ye

AU - Fraden, Seth

AU - Park, Sukho

PY - 2014/12/16

Y1 - 2014/12/16

N2 - Poly-N-isopropylacrylamide (poly-NIPAAM) has been widely used in tissue engineering and micro-structure in micro-fluidic applications. Generally, NIPAAM is polymerized and patterned by a conventional UV irradiation or UV lithography. This paper proposes a photo-polymerization method of NIPAAM using UV LED microscope. Through the combination of a commercialized UV LED, optical components, an objective lens and X-Y-Z motorized stage, we fabricated a UV LED microscope for the photo-polymerization of NIPAAM. In addition, for the investigation of the polymerization procedure, CCD camera and an illumination light source using red LED and optical components were installed. For the polymerization of NIPAAM solution, a simple micro-fluidic channel was fabricated and the NIPAAM base solution was injected into the micro-fluidic channel. If the UV LED beam was focused on the channel with NIPAAM solution, the NIPAAM can be polymerized in the focused region. Finally, we can directly fabricate micro-structures of poly-NIPAAM by using the proposed UV LED microscope.

AB - Poly-N-isopropylacrylamide (poly-NIPAAM) has been widely used in tissue engineering and micro-structure in micro-fluidic applications. Generally, NIPAAM is polymerized and patterned by a conventional UV irradiation or UV lithography. This paper proposes a photo-polymerization method of NIPAAM using UV LED microscope. Through the combination of a commercialized UV LED, optical components, an objective lens and X-Y-Z motorized stage, we fabricated a UV LED microscope for the photo-polymerization of NIPAAM. In addition, for the investigation of the polymerization procedure, CCD camera and an illumination light source using red LED and optical components were installed. For the polymerization of NIPAAM solution, a simple micro-fluidic channel was fabricated and the NIPAAM base solution was injected into the micro-fluidic channel. If the UV LED beam was focused on the channel with NIPAAM solution, the NIPAAM can be polymerized in the focused region. Finally, we can directly fabricate micro-structures of poly-NIPAAM by using the proposed UV LED microscope.

KW - LED microscope

KW - Micropatterning

KW - Photopolymerization

KW - Poly-N-isopropylacrylamide (poly-NIPAAM)

KW - UV lithography

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DO - 10.1109/ICCAS.2014.6988018

M3 - Conference contribution

AN - SCOPUS:84920180622

T3 - International Conference on Control, Automation and Systems

SP - 342

EP - 344

BT - International Conference on Control, Automation and Systems

PB - IEEE Computer Society

T2 - 2014 14th International Conference on Control, Automation and Systems, ICCAS 2014

Y2 - 22 October 2014 through 25 October 2014

ER -

Fabrication of N-isopropylacrylamide (NIPAAM) based micro-hydrogel using UV LED microscope

Abstract

Publication series

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Bibliographical note

Keywords

Access to Document

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