Expression profile analysis of trichostatin A in human gastric cancer cells

Hosoon Lee, Seongeun Lee, Myungin Bæk, Hae Yeong Kim, Doo Il Jeoung

Research output: Contribution to journalArticlepeer-review

14 Scopus citations

Abstract

Trichostatin A (TSA) is an inhibitor of histone deacetylase. cDNA microarray analysis was used to identify genes modulated by TSA. A total of 93 genes were up-regulated and 27 genes down-regulated. The expressions of some of these genes were confirmed by RT-PCR analysis.

Original languageEnglish
Pages (from-to)377-381
Number of pages5
JournalBiotechnology Letters
Volume24
Issue number5
DOIs
StatePublished - 2002

Keywords

  • Gastric cancer cell line
  • Histone deacetylase inhibitor
  • Trichostatin A (TSA)
  • cDNA microarray

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