@inproceedings{9ee81f8ec33346b984c714d90f3ee0ef,
title = "Electrical impedance spectroscopy for label-free, continuous monitoring of drug impact on 3D tissue spheroids",
abstract = "This contribution demonstrates that electrical impedance spectroscopy (EIS) can be used to detect dose- and timedependent changes in 3D microtissue properties upon drug exposure. Inhibition of growth of microtissues, derived from human colon carcinoma cells (HCT-116), upon dosage of different NaN 3 concentrations could be assessed by using a simple EIS microdevice. The same device was used to investigate the impact of Diclofenac dosage on liver (HepG2) microtissues.",
keywords = "Drug screening, Impedance spectroscopy, Tissue spheroids",
author = "B{\"u}rgel, {S. C.} and Kim, {J. Y.} and A. Hierlemann and O. Frey",
year = "2013",
language = "English",
isbn = "9781632666246",
series = "17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013",
publisher = "Chemical and Biological Microsystems Society",
pages = "1797--1799",
booktitle = "17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013",
note = "17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013 ; Conference date: 27-10-2013 Through 31-10-2013",
}