Efficient isolation and accurate in situ analysis of circulating tumor cells using detachable beads and a high-pore-density filter

Hun Joo Lee; Jin Ho Oh; Jin Mi Oh; Jong Myeon Park; Jeong Gun Lee; Minseok S. Kim; Yeon Jeong Kim; Hyun Ju Kang; Joon Jeong; Seung Il Kim; Soo Suk Lee; Jeong Woo Choi; Nam Huh

doi:10.1002/anie.201302278

Efficient isolation and accurate in situ analysis of circulating tumor cells using detachable beads and a high-pore-density filter

Hun Joo Lee
, Jin Ho Oh
, Jin Mi Oh
, Jong Myeon Park
, Jeong Gun Lee
, Minseok S. Kim
, Yeon Jeong Kim
, Hyun Ju Kang
, Joon Jeong
, Seung Il Kim
, Soo Suk Lee
, Jeong Woo Choi
, Nam Huh

Department of New Biology

Research output: Contribution to journal › Article › peer-review

81 Scopus citations

Abstract

Analysis of cancer cells: A new technique isolates rare circulating tumor cells (CTCs) and analyzes their protein expression by the use of detachable beads and high-pore-density filters. This technique shows significantly improved efficiency in the isolation of rare CTCs from peripheral blood and enables accurate measurement of in situ protein-expression levels.

Original language	English
Pages (from-to)	8337-8340
Number of pages	4
Journal	Angewandte Chemie - International Edition
Volume	52
Issue number	32
DOIs	https://doi.org/10.1002/anie.201302278
State	Published - 5 Aug 2013

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

cancer
cell capture
circulating tumor cells
in situ analysis
photolysis

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10.1002/anie.201302278

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Lee, H. J., Oh, J. H., Oh, J. M., Park, J. M., Lee, J. G., Kim, M. S., Kim, Y. J., Kang, H. J., Jeong, J., Kim, S. I., Lee, S. S., Choi, J. W., & Huh, N. (2013). Efficient isolation and accurate in situ analysis of circulating tumor cells using detachable beads and a high-pore-density filter. Angewandte Chemie - International Edition, 52(32), 8337-8340. https://doi.org/10.1002/anie.201302278

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title = "Efficient isolation and accurate in situ analysis of circulating tumor cells using detachable beads and a high-pore-density filter",

abstract = "Analysis of cancer cells: A new technique isolates rare circulating tumor cells (CTCs) and analyzes their protein expression by the use of detachable beads and high-pore-density filters. This technique shows significantly improved efficiency in the isolation of rare CTCs from peripheral blood and enables accurate measurement of in situ protein-expression levels.",

keywords = "cancer, cell capture, circulating tumor cells, in situ analysis, photolysis",

author = "Lee, \{Hun Joo\} and Oh, \{Jin Ho\} and Oh, \{Jin Mi\} and Park, \{Jong Myeon\} and Lee, \{Jeong Gun\} and Kim, \{Minseok S.\} and Kim, \{Yeon Jeong\} and Kang, \{Hyun Ju\} and Joon Jeong and Kim, \{Seung Il\} and Lee, \{Soo Suk\} and Choi, \{Jeong Woo\} and Nam Huh",

year = "2013",

month = aug,

day = "5",

doi = "10.1002/anie.201302278",

language = "English",

volume = "52",

pages = "8337--8340",

journal = "Angewandte Chemie - International Edition",

issn = "1433-7851",

publisher = "John Wiley and Sons Ltd",

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}

Lee, HJ, Oh, JH, Oh, JM, Park, JM, Lee, JG, Kim, MS, Kim, YJ, Kang, HJ, Jeong, J, Kim, SI, Lee, SS, Choi, JW & Huh, N 2013, 'Efficient isolation and accurate in situ analysis of circulating tumor cells using detachable beads and a high-pore-density filter', Angewandte Chemie - International Edition, vol. 52, no. 32, pp. 8337-8340. https://doi.org/10.1002/anie.201302278

TY - JOUR

T1 - Efficient isolation and accurate in situ analysis of circulating tumor cells using detachable beads and a high-pore-density filter

AU - Lee, Hun Joo

AU - Oh, Jin Ho

AU - Oh, Jin Mi

AU - Park, Jong Myeon

AU - Lee, Jeong Gun

AU - Kim, Minseok S.

AU - Kim, Yeon Jeong

AU - Kang, Hyun Ju

AU - Jeong, Joon

AU - Kim, Seung Il

AU - Lee, Soo Suk

AU - Choi, Jeong Woo

AU - Huh, Nam

PY - 2013/8/5

Y1 - 2013/8/5

N2 - Analysis of cancer cells: A new technique isolates rare circulating tumor cells (CTCs) and analyzes their protein expression by the use of detachable beads and high-pore-density filters. This technique shows significantly improved efficiency in the isolation of rare CTCs from peripheral blood and enables accurate measurement of in situ protein-expression levels.

AB - Analysis of cancer cells: A new technique isolates rare circulating tumor cells (CTCs) and analyzes their protein expression by the use of detachable beads and high-pore-density filters. This technique shows significantly improved efficiency in the isolation of rare CTCs from peripheral blood and enables accurate measurement of in situ protein-expression levels.

KW - cancer

KW - cell capture

KW - circulating tumor cells

KW - in situ analysis

KW - photolysis

UR - https://www.scopus.com/pages/publications/84882286406

U2 - 10.1002/anie.201302278

DO - 10.1002/anie.201302278

M3 - Article

C2 - 23825032

AN - SCOPUS:84882286406

SN - 1433-7851

VL - 52

SP - 8337

EP - 8340

JO - Angewandte Chemie - International Edition

JF - Angewandte Chemie - International Edition

IS - 32

ER -

Efficient isolation and accurate in situ analysis of circulating tumor cells using detachable beads and a high-pore-density filter

Abstract

UN SDGs

Keywords

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