Abstract
To date, various blood flow measurement systems have been presented. Recently we demonstrated multi-channel diffuse speckle contrast analysis (DSCA) to monitor in-vivo relative blood flow in deep tissues noninvasively. It has a limitation in a long-Term use due to camera contamination. Here, we present a novel fiber-lens combined DSCA which can solve it. Also it has been applied to cerebral blood flow monitoring of rats during middle cerebral artery occlusion surgery. As a result, the system showed relative changes of the flow during the arterial perfusion periods. It secures novel applications of the DSCA in in-vivo blood flow measurement.
Original language | English |
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Title of host publication | Optical Tomography and Spectroscopy of Tissue XII |
Editors | Robert R. Alfano, Eva Marie Sevick-Muraca, Bruce J. Tromberg, Arjun G. Yodh |
Publisher | SPIE |
ISBN (Electronic) | 9781510605596 |
DOIs | |
State | Published - 2017 |
Event | Optical Tomography and Spectroscopy of Tissue XII - San Francisco, United States Duration: 30 Jan 2017 → 1 Feb 2017 |
Publication series
Name | Progress in Biomedical Optics and Imaging - Proceedings of SPIE |
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Volume | 10059 |
ISSN (Print) | 1605-7422 |
Conference
Conference | Optical Tomography and Spectroscopy of Tissue XII |
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Country/Territory | United States |
City | San Francisco |
Period | 30/01/17 → 1/02/17 |
Bibliographical note
Publisher Copyright:© 2017 SPIE.
Keywords
- Blood flow index
- Cerebral blood flow
- Diffuse speckle contrast analysis
- Middle cerebral artery occlusion