Diffuse speckle contrast analysis with novel fiber-lens detection

Chaebeom Yeo, Cheol Song

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

6 Scopus citations

Abstract

To date, various blood flow measurement systems have been presented. Recently we demonstrated multi-channel diffuse speckle contrast analysis (DSCA) to monitor in-vivo relative blood flow in deep tissues noninvasively. It has a limitation in a long-Term use due to camera contamination. Here, we present a novel fiber-lens combined DSCA which can solve it. Also it has been applied to cerebral blood flow monitoring of rats during middle cerebral artery occlusion surgery. As a result, the system showed relative changes of the flow during the arterial perfusion periods. It secures novel applications of the DSCA in in-vivo blood flow measurement.

Original languageEnglish
Title of host publicationOptical Tomography and Spectroscopy of Tissue XII
EditorsRobert R. Alfano, Eva Marie Sevick-Muraca, Bruce J. Tromberg, Arjun G. Yodh
PublisherSPIE
ISBN (Electronic)9781510605596
DOIs
StatePublished - 2017
EventOptical Tomography and Spectroscopy of Tissue XII - San Francisco, United States
Duration: 30 Jan 20171 Feb 2017

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume10059
ISSN (Print)1605-7422

Conference

ConferenceOptical Tomography and Spectroscopy of Tissue XII
Country/TerritoryUnited States
CitySan Francisco
Period30/01/171/02/17

Bibliographical note

Publisher Copyright:
© 2017 SPIE.

Keywords

  • Blood flow index
  • Cerebral blood flow
  • Diffuse speckle contrast analysis
  • Middle cerebral artery occlusion

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