Dehalogenative deuteration of alkyl and aryl bromides by thiyl radical catalysis under visible-light irradiation

Jiin Lee, Sunggi Lee

Research output: Contribution to journalArticlepeer-review

Abstract

Herein, we report a mild and practical method for the deuteration of alkyl and aryl bromides by a thiyl radical catalyst and halogen-atom transfer (XAT) using disulfides and silanes under visible-light irradiation. In this study, various organic bromides such as 1°, 2°, and 3°-alkyl bromides and aryl bromides were converted to deuterated products in good to excellent yields and D-incorporation.

Original languageEnglish
Pages (from-to)5526-5529
Number of pages4
JournalChemical Communications
Volume60
Issue number42
DOIs
StatePublished - 26 Apr 2024

Bibliographical note

Publisher Copyright:
© 2024 The Royal Society of Chemistry.

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