Controlled release of guest molecules from mesoporous silica particles based on a pH-responsive polypseudorotaxane motif

Chiyoung Park, Kyoungho Oh, Sang Cheon Lee, Chulhee Kim

Research output: Contribution to journalArticlepeer-review

430 Scopus citations

Abstract

(Figure Presented) Stringing them along: The pores of a mesoporous silica particle were filled with guest molecules and then blocked by threading cyclodextrin molecules (CDs) onto the surface-grafted polyethylenimine (PEI) chains at pH 11. At pH 5.5, the guest molecules can be released from the pores of the particle by reversible dethreading of the CDs from the PEI chains.

Original languageEnglish
Pages (from-to)1455-1457
Number of pages3
JournalAngewandte Chemie - International Edition
Volume46
Issue number9
DOIs
StatePublished - 2007

Keywords

  • Cyclodextrins
  • Host-guest systems
  • Mesoporous materials
  • Rotaxanes
  • Supramolecular chemistry

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