TY - JOUR
T1 - Continuous tremor monitoring in Parkinson's disease
T2 - A wristwatch-inspired triboelectric sensor approach
AU - Ukasi, Sirinya
AU - Pongampai, Satana
AU - Panigrahi, Basanta Kumar
AU - Panda, Swati
AU - Hajra, Sugato
AU - Kim, Hoe Joon
AU - Vittayakorn, Naratip
AU - Charoonsuk, Thitirat
N1 - Publisher Copyright:
© 2024 The Author(s)
PY - 2024/12/20
Y1 - 2024/12/20
N2 - Parkinson's disease (PD) prevalence is projected to reach 12 million by 2040. Wearable sensors offer a promising approach for comfortable, continuous tremor monitoring to optimize treatment strategies. Here, we present a wristwatch-like triboelectric sensor (WW-TES) inspired by automatic watches for unobtrusive PD tremor assessment. The WW-TES utilizes a free-standing design with a surface-modified polytetrafluoroethylene (PTFE) film and a stainless-steel rotor within a biocompatible polylactic acid (PLA) package. Electrode distance is optimized to maximize the output signal. We propose and discuss the WW-TES working mechanism. The final design is validated for activities of daily living (ADLs), with varying signal amplitudes corresponding to tremor severity levels (“normal” to “severe”) based on MDS-UPDRS tremor frequency. Wavelet packet transform (WPT) is employed for signal analysis during ADLs. The WW-TES demonstrates the potential for continuous tremor monitoring, offering an accurate screening of severity and comfortable, unobtrusive wearability.
AB - Parkinson's disease (PD) prevalence is projected to reach 12 million by 2040. Wearable sensors offer a promising approach for comfortable, continuous tremor monitoring to optimize treatment strategies. Here, we present a wristwatch-like triboelectric sensor (WW-TES) inspired by automatic watches for unobtrusive PD tremor assessment. The WW-TES utilizes a free-standing design with a surface-modified polytetrafluoroethylene (PTFE) film and a stainless-steel rotor within a biocompatible polylactic acid (PLA) package. Electrode distance is optimized to maximize the output signal. We propose and discuss the WW-TES working mechanism. The final design is validated for activities of daily living (ADLs), with varying signal amplitudes corresponding to tremor severity levels (“normal” to “severe”) based on MDS-UPDRS tremor frequency. Wavelet packet transform (WPT) is employed for signal analysis during ADLs. The WW-TES demonstrates the potential for continuous tremor monitoring, offering an accurate screening of severity and comfortable, unobtrusive wearability.
KW - Health sciences
KW - Materials science
KW - Natural sciences
UR - https://www.scopus.com/pages/publications/85211145778
U2 - 10.1016/j.isci.2024.111480
DO - 10.1016/j.isci.2024.111480
M3 - Article
AN - SCOPUS:85211145778
SN - 2589-0042
VL - 27
JO - iScience
JF - iScience
IS - 12
M1 - 111480
ER -