Challenges and research directions in medical cyber-physical systems

Insup Lee, Oleg Sokolsky, Sanjian Chen, John Hatcliff, Eunkyoung Jee, Baekgyu Kim, Andrew King, Margaret Mullen-Fortino, Soojin Park, Alexander Roederer, Krishna K. Venkatasubramanian

Research output: Contribution to journalArticlepeer-review

320 Scopus citations

Abstract

Medical cyber-physical systems (MCPS) are life-critical, context-aware, networked systems of medical devices. These systems are increasingly used in hospitals to provide high-quality continuous care for patients. The need to design complex MCPS that are both safe and effective has presented numerous challenges, including achieving high assurance in system software, intoperability, context-aware intelligence, autonomy, security and privacy, and device certifiability. In this paper, we discuss these challenges in developing MCPS, some of our work in addressing them, and several open research issues.

Original languageEnglish
Article number6051465
Pages (from-to)75-90
Number of pages16
JournalProceedings of the IEEE
Volume100
Issue number1
DOIs
StatePublished - Jan 2012

Bibliographical note

Funding Information:
Manuscript received July 1, 2011; accepted August 10, 2011. Date of publication October 18, 2011; date of current version December 21, 2011. This work was supported in part by the National Science Foundation (NSF) under Grants CNS-0834524, CNS-0930647, and CNS-1035715 and by the National Institutes of Health (NIH) under Grant 1U01EB012470-01. I. Lee, O. Sokolsky, S. Chen, B. Kim, A. King, A. Roederer, and K. K. Venkatasubramanian are with the Department of Computer and Information Science, University of Pennsylvania, Philadelphia, PA 19104 USA (e-mail: [email protected]; [email protected]; [email protected]; [email protected]; [email protected]; [email protected]; [email protected]). J. Hatcliff is with the Computing and Information Sciences Department, Kansas State University, Manhattan, KS 66502 USA (e-mail: [email protected]). E. Jee is with the Computer Science Department, KAIST, Daejeon 305-701, Korea (e-mail: [email protected]). M. Mullen-Fortino and S. Park are with the Hospital of the University of Pennsylvania, Philadelphia, PA 19104 USA (e-mail: [email protected]; [email protected]).

Keywords

  • Closed-loop physiological control
  • cyber-physical systems (CPSs)
  • design challenges
  • medical device systems
  • model-based design

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