Approaching sub-ppm-level asymmetric organocatalysis of a highly challenging and scalable carbon–carbon bond forming reaction

Chemistry

• Acetal 50%
• Acid Catalysis 50%
• Aldol Reaction 50%
• Electrophile 50%
• Enantiopurity 50%
• Enantioselectivity 100%
• Enolates 50%
• Ketene 50%
• Ketone 50%
• Ketones 100%
• Lewis Acid 50%
• Mukaiyama Aldol Addition 50%
• Organic Molecule 50%
• Organocatalysis 100%
• Silyl 50%
• Silylium 50%
• Spectroscopy 50%