A novel microchip filter for rare cells separation

  • June Young Lee
  • , Hui Sung Moon
  • , Tae Seok Sim
  • , Minseok S. Kim
  • , Hyoyoung Jeong
  • , Yeon Jeong Kim
  • , Jeong Gun Lee
  • , Sanghyun Baek
  • , Jin Mi Oh
  • , Hun Joo Lee
  • , Jea Chan Park
  • , Nam Huh
  • , Soo Suk Lee

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

This paper describes a novel microchip filter device incorporating slit arrays and 3-dimensional flow that can separate rare cells with high efficiency and throughput. The proposed device has several tens of times increased throughput, and has a unique pressure distribution along the filter pore, inducing target cells to be captured and gently lined up at the end of the slit in relatively low shear stress condition. With the enhanced capture yield and throughput, the proposed device can be used as an efficient rare-cell-analyzing tool for blood-based diagnostics.

Original languageEnglish
Title of host publication2012 IEEE Nanotechnology Materials and Devices Conference, IEEE NMDC 2012
Pages88-91
Number of pages4
DOIs
StatePublished - 2012
Event2012 IEEE Nanotechnology Materials and Devices Conference, IEEE NMDC 2012 - Waikiki Beach, HI, United States
Duration: 16 Oct 201219 Oct 2012

Publication series

Name2012 IEEE Nanotechnology Materials and Devices Conference, IEEE NMDC 2012

Conference

Conference2012 IEEE Nanotechnology Materials and Devices Conference, IEEE NMDC 2012
Country/TerritoryUnited States
CityWaikiki Beach, HI
Period16/10/1219/10/12

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