A novel fully automated centrifugal microfluidic platform with massive volume capability to isolate circulating tumor cells

Minseok S. Kim, Hui Sung Moon, Sun Soo Kim, Jong Myeon Park, Nam Huh

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

2 Scopus citations

Abstract

Since circulating tumor cell(CTC) studies have shown many clinical implication, technologies enabling detection and analysis of the CTC have been briskly demonstrated. Here, we present a novel fully automated centrifugal microfluidic platform to isolate CTCs, capable of high efficient density based separation and dealing with large volume. Over 90% of cancer cells were recovered while less than 60 WBCs were remain after ∼80-minute process starting with whole blood insertion into the device.

Original languageEnglish
Title of host publication17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013
PublisherChemical and Biological Microsystems Society
Pages958-960
Number of pages3
ISBN (Print)9781632666246
StatePublished - 2013
Event17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013 - Freiburg, Germany
Duration: 27 Oct 201331 Oct 2013

Publication series

Name17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013
Volume2

Conference

Conference17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013
Country/TerritoryGermany
CityFreiburg
Period27/10/1331/10/13

Keywords

  • Cell separation
  • Centrifugal microfluidics
  • Circulating tumor cell

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