A new Butenolide Derivative from the Brown Alga Sargassum micracanthum

Ji Yul Kim; Jeong Min Lee; Hyun Soo Kim; Dae Won Ki; Mi Jin Yim; Seok Chun Ko; Jung Min Shin; Myeong Seok Lee; Yun Gyeong Park; Dae Sung Lee

doi:10.1177/1934578X211068606

A new Butenolide Derivative from the Brown Alga Sargassum micracanthum

Ji Yul Kim
, Jeong Min Lee
, Hyun Soo Kim
, Dae Won Ki
, Mi Jin Yim
, Seok Chun Ko
, Jung Min Shin
, Myeong Seok Lee
, Yun Gyeong Park
, Dae Sung Lee

Division of Biotechnology

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

Abstract

A new butenolide derivative (1), along with three known compounds (2-4) were isolated from the MeOH extract of brown alga Sargassum micracanthum. The structures of 1 to 4 were determined by the analyses of 1D and 2D NMR and mass spectroscopic data. The known compounds (2-4) were identified as (5E,10Z)-6,10,14-trimethylpentadeca-5,10-dien-2,12-dione (2), (5E,9E)-6,10,14-trimethylpentadeca-5,9-dien-2,12-dione (3), and (-)-loliolide (4) by comparing with their published spectroscopic data. The antioxidant activities of compounds 1 to 4 were evaluated based on using 2,2′-azinobis-(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) and 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging activities. Compounds 1 to 4 were inactive at the concentration of 200 μM.

Original language	English
Journal	Natural Product Communications
Volume	17
Issue number	1
DOIs	https://doi.org/10.1177/1934578X211068606
State	Published - Jan 2022

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Publisher Copyright:
© The Author(s) 2022.

Keywords

NMR
Sargassum micracanthum
brown alga
butenolide

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10.1177/1934578X211068606

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@article{903daf17570143889051d68f1f095b99,

title = "A new Butenolide Derivative from the Brown Alga Sargassum micracanthum",

abstract = "A new butenolide derivative (1), along with three known compounds (2-4) were isolated from the MeOH extract of brown alga Sargassum micracanthum. The structures of 1 to 4 were determined by the analyses of 1D and 2D NMR and mass spectroscopic data. The known compounds (2-4) were identified as (5E,10Z)-6,10,14-trimethylpentadeca-5,10-dien-2,12-dione (2), (5E,9E)-6,10,14-trimethylpentadeca-5,9-dien-2,12-dione (3), and (-)-loliolide (4) by comparing with their published spectroscopic data. The antioxidant activities of compounds 1 to 4 were evaluated based on using 2,2′-azinobis-(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) and 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging activities. Compounds 1 to 4 were inactive at the concentration of 200 μM.",

keywords = "NMR, Sargassum micracanthum, brown alga, butenolide",

author = "Kim, \{Ji Yul\} and Lee, \{Jeong Min\} and Kim, \{Hyun Soo\} and Ki, \{Dae Won\} and Yim, \{Mi Jin\} and Ko, \{Seok Chun\} and Shin, \{Jung Min\} and Lee, \{Myeong Seok\} and Park, \{Yun Gyeong\} and Lee, \{Dae Sung\}",

note = "Publisher Copyright: {\textcopyright} The Author(s) 2022.",

year = "2022",

month = jan,

doi = "10.1177/1934578X211068606",

language = "English",

volume = "17",

journal = "Natural Product Communications",

issn = "1934-578X",

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T1 - A new Butenolide Derivative from the Brown Alga Sargassum micracanthum

AU - Kim, Ji Yul

AU - Lee, Jeong Min

AU - Kim, Hyun Soo

AU - Ki, Dae Won

AU - Yim, Mi Jin

AU - Ko, Seok Chun

AU - Shin, Jung Min

AU - Lee, Myeong Seok

AU - Park, Yun Gyeong

AU - Lee, Dae Sung

PY - 2022/1

Y1 - 2022/1

N2 - A new butenolide derivative (1), along with three known compounds (2-4) were isolated from the MeOH extract of brown alga Sargassum micracanthum. The structures of 1 to 4 were determined by the analyses of 1D and 2D NMR and mass spectroscopic data. The known compounds (2-4) were identified as (5E,10Z)-6,10,14-trimethylpentadeca-5,10-dien-2,12-dione (2), (5E,9E)-6,10,14-trimethylpentadeca-5,9-dien-2,12-dione (3), and (-)-loliolide (4) by comparing with their published spectroscopic data. The antioxidant activities of compounds 1 to 4 were evaluated based on using 2,2′-azinobis-(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) and 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging activities. Compounds 1 to 4 were inactive at the concentration of 200 μM.

AB - A new butenolide derivative (1), along with three known compounds (2-4) were isolated from the MeOH extract of brown alga Sargassum micracanthum. The structures of 1 to 4 were determined by the analyses of 1D and 2D NMR and mass spectroscopic data. The known compounds (2-4) were identified as (5E,10Z)-6,10,14-trimethylpentadeca-5,10-dien-2,12-dione (2), (5E,9E)-6,10,14-trimethylpentadeca-5,9-dien-2,12-dione (3), and (-)-loliolide (4) by comparing with their published spectroscopic data. The antioxidant activities of compounds 1 to 4 were evaluated based on using 2,2′-azinobis-(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) and 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging activities. Compounds 1 to 4 were inactive at the concentration of 200 μM.

KW - NMR

KW - Sargassum micracanthum

KW - brown alga

KW - butenolide

UR - https://www.scopus.com/pages/publications/85122523859

U2 - 10.1177/1934578X211068606

DO - 10.1177/1934578X211068606

M3 - Article

AN - SCOPUS:85122523859

SN - 1934-578X

VL - 17

JO - Natural Product Communications

JF - Natural Product Communications

IS - 1

ER -

A new Butenolide Derivative from the Brown Alga Sargassum micracanthum

Abstract

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