A microfluidic in vitro cultivation system to mimic event of in vivo oviductal peristalsis

  • Chae Yun Bae
  • , Minseok S. Kim
  • , Gabbine Wee
  • , Yong Mahn Han
  • , Je Kyun Park

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

In this study, a novel microfluidic in vitro cultivation (IVC) system is presented for improving embryonic development within a constricted channel that mimics peristaltic muscle contraction. Bovine embryos were loaded and dynamically incubated by a tilting machine that supports embryo movement via gravity. The in vitro fertilized embryos could be cultivated on the microfluidic IVC system until the blastocyst, hatching or hatched blastocysts. This suggests the possibility of peristaltic stimulation for the early development of bovine embryos in assistedreproduction research.

Original languageEnglish
Title of host publicationProceedings of Conference, MicroTAS 2009 - The 13th International Conference on Miniaturized Systems for Chemistry and Life Sciences
PublisherChemical and Biological Microsystems Society
Pages567-569
Number of pages3
ISBN (Print)9780979806421
StatePublished - 2009
Event13th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2009 - Jeju, Korea, Republic of
Duration: 1 Nov 20095 Nov 2009

Publication series

NameProceedings of Conference, MicroTAS 2009 - The 13th International Conference on Miniaturized Systems for Chemistry and Life Sciences

Conference

Conference13th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2009
Country/TerritoryKorea, Republic of
CityJeju
Period1/11/095/11/09

Keywords

  • Bovine embryos
  • In vitro cultivation
  • Mechanical stimulation
  • Microfluidics
  • Peristalsis

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