A high throughput screening platform to rejuvenate skeletal muscle function via electrical stimulation

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

Sarcopenia is the disease owing to loss of muscle tissue as a natural part of the aging process and it has not yet developed drugs. Unfortunately, although exercise is the only way to treat sarcopenia, it is sometimes difficult for elderly people to exercise by various inconvenient body conditions. While many studies have been done to apply electrical stimulation (ES) as an alternative intervention of exercise, there are still unmet demands to investigate the effect of precise and systemic ES for skeletal muscle cells (skMC) as well as to explore the behavior of aged skMC. As such, we developed a novel ES-based high throughput screening platform to quantitatively search the ES effect for skMC. Using this platform, we could see the possibility to improve the functions of old skMC cells via ES.

Original languageEnglish
Title of host publication23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019
PublisherChemical and Biological Microsystems Society
Pages534-535
Number of pages2
ISBN (Electronic)9781733419000
StatePublished - 2019
Event23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019 - Basel, Switzerland
Duration: 27 Oct 201931 Oct 2019

Publication series

Name23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019

Conference

Conference23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019
Country/TerritorySwitzerland
CityBasel
Period27/10/1931/10/19

Bibliographical note

Publisher Copyright:
© 2019 CBMS-0001.

Keywords

  • Electrical stimulation
  • Human skeletal muscle cell
  • Rejuvenation
  • Sarcopenia

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