Abstract
This paper presents the simple and robust 96-well format-based microfluidic platforms and tilting tower system (TTS) for multi-3D microtissue (MT) experiment in a high-throughput manner. The in-vitro network of multiple organotypic MTs can be realized by physically separating MTs but fluidically interconnecting them in the microfluidic platform. The TTS enables long-term cultivation of the in-vitro MTs network under perfusion condition in an incubator without any external tubing and pumps. It allows to easily host various type of organotypic 3D MTs in a straightforward and high-throughput manner and can be also highly compatible with the existing laboratory automation equipment such as robot arms for microplates.
| Original language | English |
|---|---|
| Title of host publication | 22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018 |
| Publisher | Chemical and Biological Microsystems Society |
| Pages | 1652-1654 |
| Number of pages | 3 |
| ISBN (Electronic) | 9781510897571 |
| State | Published - 2018 |
| Event | 22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018 - Kaohsiung, Taiwan, Province of China Duration: 11 Nov 2018 → 15 Nov 2018 |
Publication series
| Name | 22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018 |
|---|---|
| Volume | 3 |
Conference
| Conference | 22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018 |
|---|---|
| Country/Territory | Taiwan, Province of China |
| City | Kaohsiung |
| Period | 11/11/18 → 15/11/18 |
Bibliographical note
Publisher Copyright:Copyright © (2018) by Chemical and Biological Microsystems Society. All rights reserved.
Keywords
- 3D cell culture
- In-vitro micro-organ network
- Microfluidics
- Microtissue
- Spheroid