Personal profile
Education
- 2008 Ph.D., University of Michigan
- 2001 M.S., Seoul National Universtiy
- 1996 B.S., Seoul National Universtiy
- 2001 M.S., Seoul National Universtiy
- 1996 B.S., Seoul National Universtiy
Professional Experience
- 2009 Research fellow, University of Michigan
- 2010-2016 Research fellow, Boston Children’s Hospital/Harvard Medical School
- 2016-2022 Assistant professor, Department of New Biology, DGIST
- 2022-present Associate professor, Department of New Biology, DGIST
- 2010-2016 Research fellow, Boston Children’s Hospital/Harvard Medical School
- 2016-2022 Assistant professor, Department of New Biology, DGIST
- 2022-present Associate professor, Department of New Biology, DGIST
Research Interests
- Cellular stress and its associated signaling regulation
- Insulin and leptin signaling
- Metabolism and metabolic diseases (diabetes, obesity)
- Aging and its associated metabolic diseases
- Insulin and leptin signaling
- Metabolism and metabolic diseases (diabetes, obesity)
- Aging and its associated metabolic diseases
Major Research Achievements
- Park, B.G., Kim, G.M., Lee, H-J., Ryu, J.H., Kim, D-H., Seong, J-Y., Kim, S., Park, Z-Y., Kim, Y-J., Lee, Jaemin*, Kim, J.I.*. Anti-obesity therapeutics with complementary dual-agonist activities at glucagon and glucagon-like peptide 1 receptors. Diabetes, Obesity and Metabolism 2022. 24(1):50-60. *co-corresponding authors.
- Lee, Jaemin*, Salazar Hernandez, M.A., Auen, T., Mucka, P., Lee, J., Ozcan, U*. PGC-1α functions as a co-suppressor of XBP1s to regulate glucose metabolism. Molecular Metabolism 2018, 7:119-131. *co-corresponding authors.
- Lee, Jaemin*, Liu, J.*, Feng, X.*, Salazar Hernandez, M.A., Mucka, P., Ibi, D., Choi, J-W., Ozcan, U. Withaferin A is a Leptin Sensitizer with Strong Anti-diabetic Properties in Mice. Nature Medicine 2016, 22(9): 1023-1032. *co-first authors.
- Liu, J.*, Lee, Jaemin*, Salazar Hernandez, M.A., Mazitschek, R. Ozcan, U. Treatment of obesity with celastrol. Cell 2015, 161(5): 999-1011. * co-first authors
- Lee, Jaemin, Ozcan, U. Unfolded protein response signaling and metabolic diseases. Journal of Biological Chemistry 2014, 289(3): 1203-1211.
- Lee, Jaemin*, Salazar Hernandez, M.A., Auen, T., Mucka, P., Lee, J., Ozcan, U*. PGC-1α functions as a co-suppressor of XBP1s to regulate glucose metabolism. Molecular Metabolism 2018, 7:119-131. *co-corresponding authors.
- Lee, Jaemin*, Liu, J.*, Feng, X.*, Salazar Hernandez, M.A., Mucka, P., Ibi, D., Choi, J-W., Ozcan, U. Withaferin A is a Leptin Sensitizer with Strong Anti-diabetic Properties in Mice. Nature Medicine 2016, 22(9): 1023-1032. *co-first authors.
- Liu, J.*, Lee, Jaemin*, Salazar Hernandez, M.A., Mazitschek, R. Ozcan, U. Treatment of obesity with celastrol. Cell 2015, 161(5): 999-1011. * co-first authors
- Lee, Jaemin, Ozcan, U. Unfolded protein response signaling and metabolic diseases. Journal of Biological Chemistry 2014, 289(3): 1203-1211.
URL
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Engineered extracellular vesicles with surface FGF21 and enclosed miR-223 for treating metabolic dysfunction-associated steatohepatitis
Cho, H., Ju, H., Ahn, Y., Jang, J., Cho, J., Park, E., Kang, S. M., Lee, J., Seo, D., Baek, M. C. & Yea, K., Oct 2025, In: Biomaterials. 321, 123321.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
Neurotherapeutic effects of Vutiglabridin as a Paraoxonase-2 modulator in preclinical models of Parkinson’s disease
An, H., Kang, S., Shin, J., Kim, P., Kim, S., Im, S., Kim, J. H., Lee, K. W., Kim, D. H., Park, J. H., Park, M. H., Lee, J., Park, S. K., Kim, K. P., Lee, H. M., Lee, J. H., Choi, L. S., Jeon, H. J., Kim, S. Y. & Hwang, I. Y. & 7 others, , Dec 2025, In: Molecular Neurodegeneration. 20, 1, 110.Research output: Contribution to journal › Article › peer-review
Open Access -
ER stress and unfolded protein response (UPR) signaling modulate GLP-1 receptor signaling in the pancreatic islets
Gao, Y., Ryu, H., Lee, H., Kim, Y. J., Lee, J. H. & Lee, J., Jan 2024, In: Molecules and Cells. 47, 1, 100004.Research output: Contribution to journal › Article › peer-review
Open Access16 Scopus citations -
Exploring Renal Pyruvate Metabolism as a Therapeutic Avenue for Diabetic Kidney Injury
Lee, J., May 2024, In: Diabetes and Metabolism Journal. 48, 3, p. 385-386 2 p.Research output: Contribution to journal › Editorial
Open Access3 Scopus citations -
Lithium and exercise ameliorate insulin-deficient hyperglycemia by independently attenuating pancreatic α-cell mass and hepatic gluconeogenesis
Jung, S. R., Lee, J. H., Ryu, H., Gao, Y. & Lee, J., Jan 2024, In: Korean Journal of Physiology and Pharmacology. 28, 1, p. 31-38 8 p.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations
Press/Media
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Study Data from Daegu Gyeongbuk Institute of Science and Technology (DGIST) Provide New Insights into Chalcogens (Hydrogen diffusion and its electrical properties variation as a function of the IGZO stacking structure)
Lee, M.-J., Kim, J.-S., Lee, H.-J., Lee, J., Lee, J. & Lee, J.
7/12/22
1 item of Media coverage
Press/Media